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Updated: Feb 3, 2026

Preparation of Neutrally-charged, pH-responsive Polymeric Nanoparticles for Cytosolic siRNA Delivery
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装有TAK1抑制剂的充电转换纳米粒子抑制了视网膜新血管化

Xingbo Teng1,2, Zhiqing Yuan1, Mengyun Li1

  • 1Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou, China.

Journal of nanobiotechnology
|February 1, 2026
PubMed
概括

转化生长因子-β (TGF-β) 激活激酶1 (TAK1) 驱动视网膜新血管化 (RNV). 一个新的纳米粒子系统有效地抑制TAK1,降低RNV,并为致盲眼病提供了一种新的治疗策略.

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