三甘油糖指数及其相关参数与手握强度不对称的关联
Yuan Zhang1,2, Yali Jing1,2
1Department of Endocrinology, Endocrine and Metabolic Disease Medical Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Journal of cachexia, sarcopenia and muscle
|February 2, 2026
概括
较高的甘油三糖腰高比 (TyG-WHtR) 与手握强度不对称性 (HGS-A) 的增加有关,而较高的甘油三糖体质指数 (TyG-BMI) 在中国老年人中显示出保护作用.
科学领域:
- 老年学是指老年学的学科.
- 代谢健康 代谢健康
- 生物识别信息 生物识别信息
背景情况:
- 手握强度不对称 (HGS-A) 是老年人健康状况的潜在指标.
- 甘油三糖 (TyG) 指数及其衍生品 (TyG-BMI,TyG-WHtR) 反映了代谢功能障碍.
- 代谢标志物和HGS-A之间的关联需要在不同人群中进一步调查.
研究的目的:
- 调查TyG指数及其衍生品 (TyG-BMI,TyG-WHtR) 和HGS-A.之间的关系.
- 在45-80岁的全国代表性中国成年人群中分析这些关联.
主要方法:
- 利用了2015年中国健康与退休长度研究 (CHARLS) 的数据.
- 定义的HGS不对称性基于非主导与主导手握强度的比例.
- 使用多变量逻辑回归来评估TyG,TyG-BMI,TyG-WHtR和HGS不对称性之间的关联.
主要成果:
- 包括3521名参与者 (平均年龄59.74岁).
- 较高的TyG-WHtR四分位数与严重HGS不对称的患病率增加相关 (p=0.042).
- 较高的TyG-BMI四分位数与严重的HGS不对称性患病率 (p<0.05) 有相反的关联.
- TyG-WHtR (Q2,Q3) 与明显增加的不对称率相关 (OR=1.507,1.437).
- TyG-BMI显示出一种保护作用,较高的四分位数与减少的几率有关 (Q2-Q4 OR范围:0.973-0.984).
结论:
- 提升的TyG-WHtR与更高的HGS不对称的患病率和严重程度有关.
- 降低的TyG-BMI与HGS不对称的发病率和严重程度较低有关.
- 这些代谢指数提供了关于老龄化人口肌肉力量差异的见解.
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