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相关概念视频

Sign Convention01:30

Sign Convention

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When analyzing a beam subjected to various loads, it is crucial to understand the internal forces and moments generated within the structure. These internal forces can be broadly classified into normal forces, shear forces, and bending moments. To determine these forces and moments, we use the method of sections and apply a specific sign convention based on their direction and the side of the section being analyzed.
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Enolate Mechanism Conventions01:15

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When a carbonyl compound is treated with a strong base, the α position gets deprotonated to give a resonance-stabilized intermediate called an enolate. Enolates are ambident nucleophiles because they possess two nucleophilic sites that can attack an electrophile owing to the delocalization of the negative charge between the α carbon and oxygen atoms. When the oxygen atom attacks an electrophile, it is called O-attack, whereas electrophilic attack via the α carbon is known as...
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Protein Complex Assembly02:41

Protein Complex Assembly

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Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
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Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
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Complex Numbers01:29

Complex Numbers

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The real number system cannot represent the square root of a negative number, which restricts solutions for certain equations, such as quadratics with negative discriminants. To address this, the complex number system was developed, introducing the imaginary unit i, where i = √(-1). This extension allows for the representation of all roots, including those involving negative radicands.A complex number is written in the form x + yi, where x and y are real numbers. Here, x represents the...
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Aortic Regurgitation I: Introduction

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IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
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相关实验视频

Updated: Feb 3, 2026

Three-Dimensional Printing of a Complex Aortic Anomaly
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在复杂的大动脉外科手术中,迷你椎切除术与传统的椎切除术相比.

Omar A Jarral1, Stevan S Pupovac1, Adam Kiridly1

  • 1Department of Cardiothoracic Surgery, Northwell Cardiovascular Institute, New Hyde Park, NY, USA.

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概括

至少侵入性的迷你切除术是对选择近道大动脉手术的安全方法. 结果,包括死亡率和中风,与传统方法相比,支持其在复杂病例中的有效性.

关键词:
大动脉的动脉.大动脉门置换大动脉根替代术最小的访问手术手术.部长进行了切除术.门节约根部的更换

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科学领域:

  • 心血管外科心血管外科
  • 胸部外科手术 胸部外科手术
  • 最少侵入性的手术

背景情况:

  • 靠近大动脉的手术传统上涉及到中枢管切除.
  • 至少侵入性的方法,如 ministernotomy,正在获得引力.
  • 对复杂的大动脉手术进行 ministernotomy 的结果进行评估至关重要.

研究的目的:

  • 通过 ministernotomy 方法评估近端大动脉手术的机构结果.
  • 在特定的大动脉手术中,比较 ministernotomy 和常规大动脉手术之间的结果.

主要方法:

  • 对前性维护数据库 (2015-2021) 的回顾性分析.
  • 包括接受选择性近道大动脉手术的成年患者,但不包括特定复杂病例.
  • 多变量回归分析,以评估手术方法对复合结果 (死亡率,中风,功能衰竭,重新手术) 和二次结果 (输血,停留时间) 的影响.

主要成果:

  • 在547名患者中,有74名患者 (13.5%) 接受了迷宫切除术.
  • 对于死亡率,中风,功能衰竭和住院治疗的未经调整的结果在各组之间是相似的.
  • 在 ministernotomy 组中,血液出血和输血的再手术率较高,可能是由于同时进行的门手术和学习曲线效应.
  • 多变量分析显示, ministernotomy 与初级或二级结果之间没有显著的关联.

结论:

  • 迷宫切除术是一种安全有效的手术方法,用于接受复杂近道大动脉手术的选定患者.
  • 这些发现有助于越来越多的证据支持微创性大动脉手术.
  • 该研究强调了在复杂的近道主动脉手术中 ministernotomy 的可行性.