认知储备和空气污染混合物对没有痴呆症的成年人认知功能的影响
Juyeon Ko1, Young Noh2, Sang-Baek Koh3
1Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Psychological medicine
|February 2, 2026
概括
较高的认知储备可以防止空气污染对认知功能的负面影响. 这项研究发现,具有较大的认知储备的人在暴露于空气污染时,认知衰退较少.
科学领域:
- 环境健康 环境健康
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 空气污染暴露与认知能力下降有关.
- 认知储备和大脑储备的调节作用仍然不清楚.
- 这项研究调查了认知和大脑储备如何影响空气污染-认知功能关系.
研究的目的:
- 检查认知储备贡献者和大脑储备的调节作用.
- 评估空气污染与没有痴呆症的成年人的认知功能之间的关联.
主要方法:
- 对650名参与者进行脑部MRI和认知评估 (MoCA) 的横截面研究.
- 通过教育,职业和社会参与来评估认知储备.
- 大脑储备量化为心室与大脑的比例;空气污染暴露量按居住地址估计.
- 用于分析认知和大脑储备的缓解效应的统计建模.
主要成果:
- 增加的空气污染与较低的MoCA分数有关.
- 这种关联在具有较高认知储备的人群中减弱,而在具有较低认知储备的人群中加剧.
- 大脑储备并没有显著缓解这种关联.
结论:
- 更高的认知储备可能会减轻空气污染对认知功能的负面影响.
- 通过教育,职业和社会参与建立的认知储备,提供了对环境认知威胁的保护作用.
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