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Updated: Feb 3, 2026

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提高循环L-Kynurenine促进衰老老鼠的脆弱性

Mia Y Kawaida1, Abigail L Tice1, Samuel Alvarez1

  • 1Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.

Journal of cachexia, sarcopenia and muscle
|February 2, 2026
PubMed
概括

升高的L-Kynurenine (L-Kyn) 会使衰老的脆弱性恶化,但骨肌肉的PGC1α过度表达可以防止这种衰退. 这种保护与肌肉 kynurenine 氨基转移酶 (KAT) 表达和代谢的增加有关.

关键词:
老化的老化 衰老的老化脆弱 脆弱 脆弱 脆弱 脆弱线粒体中的线粒体.肌肉 肌肉 肌肉 肌肉 肌肉身体功能 身体功能 身体功能

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