大肠直肠器官在组织工程中的不断变化的景观:研究趋势和热点
Huiping Gan1, Pan Huang2, Jia Wang2
1Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, China.
Tissue engineering. Part C, Methods
|February 2, 2026
概括
结肠直肠器官正在彻底改变研究,从基本生物学发展到疾病建模和个性化医学. 未来的工作将改进有机体培养,并扩大临床应用,特别是患者衍生有机体.
科学领域:
- * 生物医学研究
- * 发育生物学 发育生物学
- * 胃肠病学 胃肠病学
背景情况:
- *结肠直肠器官精确地模拟了人类结肠直肠上皮的结构和功能.
- *它们是生物研究和临床应用的关键平台.
- *图书统计分析为结直肠器官研究的知识领域提供了洞察力.
研究的目的:
- * 通过图书统计分析创建结直肠器官研究的知识领域地图.
- * 检查研究主题,焦点,并确定未来的研究方向.
- *分析出版趋势,主要贡献者和新兴研究领域.
主要方法:
- *来源于"科学网络核心集合" (2010-2025) 的文章.
- * 已使用CiteSpace 6.3.R1进行文献计量分析.
- *分析了出版物成果,期刊,国家,机构,作者,共同引用,引用,共同出现的术语和突发术语.
主要成果:
- * 2010年至2025年间发表的719篇文章.
- * *自然通讯*是主要的期刊;美国和乌得勒支大学是最多产的国家和机构.
- *汉斯·克利弗斯是最多产的作者;托希罗·萨托领先于共.
结论:
- *研究重点已经从基本特征转移到疾病建模,临床应用,功能机制和精密医学.
- *关键的新兴领域包括患者衍生器官,疾病建模,上皮屏障研究和个性化医学.
- *结肠直肠器官研究是一个重要的跨学科领域,具有未来临床翻译的巨大潜力.
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