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Updated: Feb 3, 2026

Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability
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林/侧链C-H/O相互作用稳定了cis-林

Harrison C Oven1, Himal K Ganguly1, Neal J Zondlo1

  • 1Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA. zondlo@udel.edu.

Physical chemistry chemical physics : PCCP
|February 2, 2026
PubMed
概括

C-H/O 相互作用稳定了蛋白质中的 cis-proline 构造,特别是在 Glu-Pro 序列. 这些相互作用对于素和三素残留物也至关重要.

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