扩散权重磁共振成像和明显扩散系数映射检测脏透在急性髓性白血病:一个案例报告
Yusuke Yoshimura1, Yuki Oba1, Kei Kono2
1Nephrology Center, Toranomon Hospital Kajigaya, Kanagawa, Japan.
Kidney medicine
|February 2, 2026
概括
磁共振成像 (MRI) 有助于诊断急性髓性白血病 (AML) 的罕见脏透. 这个案例突出显示了MRI.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 血液学 血液学 血液学
- 放射学 放射学是指放射学
背景情况:
- 急性髓性白血病 (AML) 很少会透到脏,表现为非特异性症状,经常被计算机断层扫描 (CT) 遗漏.
- 早期诊断脏透对于有效治疗和管理血液恶性瘤至关重要.
研究的目的:
- 报告急性髓性白血病 (AML) 病例,诊断出脏透,使用磁共振成像 (MRI).
- 强调扩散加权成像 (DWI) 和明显扩散系数 (ADC) 映射在检测脏爆细胞透中的诊断实用性.
主要方法:
- 一名70岁的男性患有2型糖尿病和骨髓质疏松综合征,进展为AML,呈现急性损伤.
- 脏MRI显示了特征性发现 (高DWI,低ADC) 暗示透,通过活检证实.
- 用venetoclax和azacitidine治疗导致AML缓解和功能恢复.
主要成果:
- 核磁共振,特别是DWI和ADC映射,成功地确定了脏中的爆细胞透,CT上没有明显的情况.
- 脏活检证实了脏囊和近端管道的白血病透.
- 患者经过向治疗后,AML和功能迅速改善.
结论:
- 核磁共振,特别是DWI和ADC映射,是诊断AML脏透的有价值的非侵入性工具,特别是当CT不确时.
- 这一案例强调了在患有血液性恶性瘤和无法解释的功能障碍的患者中考虑高级成像的重要性.
- 早期检测和治疗AML的内透可以显著改善患者的结果.
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