一个基于区块链的框架,包含零知识证明,用于通过健康记录系统安全共享基因组数据
Nandini Krishappa1, Girisha Gowdra Shivappa1, Sharon Zachariah1
1Department of Computer Science and Engineering, Dayananda Sagar University, Bengaluru South, Karnataka, India.
Blockchain in healthcare today
|February 2, 2026
概括
这项研究引入了使用零知识证明 (ZKP) 的区块链框架,用于在精准医学中安全共享基因组数据,增强隐私并使医疗保健研究能够有效访问数据.
科学领域:
- 基因组学就是基因组学.
- 区块链技术 区块链技术
- 密码学 密码学 密码学 密码学
- 医疗信息学 医疗信息学
背景情况:
- 基因组数据共享对于精准医学至关重要,但由于基因组信息的敏感性和不变性,它面临着重大隐私和安全挑战.
- 现有的健康记录系统在努力平衡数据可访问性和对高度敏感的基因组数据集的强有力的隐私保护.
研究的目的:
- 提出和评估一种基于区块链的新型框架,用于在健康记录系统中安全和保护隐私的基因组数据共享.
- 利用零知识证明 (ZKP),智能合约和离链存储来促进对敏感基因组数据的受控访问.
主要方法:
- 在模拟的基因组数据集上使用Python开发概念验证原型.
- 实现一个混合存储系统,用于元数据的区块链和用于加密数据的星际文件系统 (IPFS).
- 集成基于规则的访问控制和ZKP的智能合约与圆曲线加密 (ECC) 实现隐私和安全.
主要成果:
- 该框架展示了平均零知识证明与区块链 (ZKPB) 查询延迟时间为5.83ms,准确率为90.00%.
- 智能合约和区块链查询延迟时间低于0.01ms,准确率为90.00%.
- 圆曲线加密 (ECC) 延迟平均为8.72ms,准确率为90.00%,验证了框架的效率和隐私.
结论:
- 拟议的区块链框架有效地促进了安全,保护隐私的基因组数据共享.
- 该框架的性能指标验证了其在医疗保健研究,临床基因组学和个性化医学中的潜在用途.
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