在海洋水柱中,来自 prokaryotes 的小蛋白质,在海洋的全部深度
Qing-Mei Li1,2, Li-Sheng He1, Yong Wang3,4
1Institute of Deep-Sea Science and Engineering, Chinese Academy of Sciences, Sanya, Hainan 572000, P.R. China.
iScience
|February 2, 2026
概括
这项研究揭示了小蛋白质 (SPs) 对于深海中 prokaryotic 适应至关重要. 许多独特于海洋环境的新型SP被转录,可能有助于对抗深海压力因素的生存.
科学领域:
- 海洋微生物学 海洋微生物学
- 基因组学就是基因组学.
- 原体生物学的生物学
背景情况:
- 小蛋白 (SPs) 在基因组研究中经常被忽视.
- Prokaryotic 适应极端环境,如深海并没有完全理解.
研究的目的:
- 通过海洋深度梯度对 prokaryotic 小蛋白进行第一个系统分析.
- 识别新型SP并了解它们在海洋生态系统中的分布和潜在功能.
主要方法:
- 来自71个西太平洋元基因组的小开放阅读框架 (sORF) 的预测.
- 聚类和过以确定流行和高可信度SP (RfSP).
- 对同类的分析,域组成,遗传学分布和共发生模式.
- 通过深海元转录学证实了转录.
主要成果:
- 确定了193,281个SP集群,有75,581个流行SP,其中包括4,307个高可信度RfSP.
- 87.09%的RfSP缺乏非海洋同类,约70%含有未知域,表明新性.
- 12个RfSP分布在≥5个族群中,23个核心RfSP普遍存在.
- 在深海元转录组中确认了8.20%的RfSP集群的转录,并观察到特定区域的模式.
结论:
- Prokaryotic 小蛋白质代表了一个重要的,低估的战略适应深海条件.
- 新型和保存的SP在应激反应和分子监护中发挥作用,促进在各种海洋区域的生存.
- 这项工作强调了探索SPs对于了解极端海洋环境中的微生物生命的重要性.
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