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Updated: Feb 4, 2026

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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Published on: July 25, 2019

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惠普1β招募RING1A到全方位基因组H2A,用于BRCA1介导的双杆断裂的切除

Vijaya Charaka1,2, Raj K Pandita1,3, Chi-Lin Tsai4

  • 1Department of Radiation Oncology, The Houston Methodist Research Institute, Houston, TX 77030, USA.

iScience
|February 2, 2026
PubMed
概括

异染色素蛋白1β (HP1β) 对于DNA修复至关重要,它通过促进BRCA1在基因丰富区域的双链断裂部位的丰富. 这种相互作用促进了基因组的稳定性和预防癌症.

关键词:
生物化学 生物化学分子生物学分子生物学

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