应对和管理抗生素短缺:与专家和论领袖进行的定性研究
Vrinda Nampoothiri1, Ritika Kondel Bhandari2, Avaneesh Kumar Pandey2
1Department of Infection Control and Epidemiology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Wellcome open research
|February 2, 2026
概括
抗生素短缺源于复杂的供应链问题. 解决这些问题需要政治参与,经济激励和技术进步,以确保对基本药物的持续获取.
科学领域:
- 制药科学 制药科学
- 公共卫生 公共卫生
- 供应链管理 供应链管理
背景情况:
- 调查当前授权抗生素短缺的主要驱动因素.
- 审查现有的减缓战略及其实施障碍.
研究的目的:
- 确定导致抗生素短缺的关键因素.
- 评估目前管理这些短缺的战略.
- 了解实施有效解决方案的障碍.
主要方法:
- 在欧洲,南非,印度和美国的专家采访 (n=16) 中使用了有目的的抽样.
- 采用基于PESTELI框架 (政治,经济,社会,生态,技术,法律,工业) 的半结构面试指南.
- 通过使用恒定比较进行代数据收集和分析.
主要成果:
- 政治参与和政府投资对于有效的减缓战略至关重要.
- 正在利用法律措施,如自动替代和要求制造透明度等.
- 缺乏经济激励因素阻碍了制药行业的参与;在短缺预测和管理方面存在技术差距.
- 社会因素,比如沟通以防止恐慌购买,是很重要的.
结论:
- 目前针对抗生素短缺的干预措施有限.
- 抗生素供应链是复杂的,受到PESTELI因素的影响,需要特定的环境缓解.
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