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在延迟 vs 立即放置的牙科植入物中对周围植入物状微生物的比较分析
Nikunj Harikrushn Prajapati1, Malav Sunilbhai Sheth2, Abhishek Singh Payak3
1Department of Orthodontics and Dentofacial Orthopedics, Siddhpur Dental College & Hospital, Patan, Gujarat, India.
Bioinformation
|February 2, 2026
概括
植入牙的时间会影响口腔微生物群的发展. 延迟植入物放置早期显示了更高水平的有害细菌,这表明植入周边问题的风险增加.
科学领域:
- 口腔微生物学 口腔微生物学
- 牙科植入物学 牙科植入物学
- 牙周病学 牙周病学
背景情况:
- 植入牙的时间是可能影响早期微生物殖民的关键因素.
- 了解植入周微生物群的动态对于长期植入成功和患者健康至关重要.
研究的目的:
- 为了比较即时和延迟单牙植入物放置之间的状微生物组成.
- 调查植入物安置时间对12个月的早期微生物殖民和潜在失生症的影响.
主要方法:
- 一项前性队列研究,涉及60名单一牙植入的患者 (30名立即,30名延迟).
- 在基线,3,6和12个月后使用16SrRNA测序分析状微生物群的分析.
- 立即和延迟植入组之间的微生物特征的统计比较.
主要成果:
- 立即植入物最初在3个月内含有更高水平的开始性口腔属.
- 延迟植入物在6个月后显著增加了牙周病原体的殖民,包括 Porphyromonas gingivalis 和 Tannerella forsythia,在6个月后 (p<0.05).
- 群体之间的微生物差异减少了12个月,致病物种的趋同.
结论:
- 延迟植入牙似乎与对早期口腔失生症的更高易感性有关.
- 这些发现强调了细致的斑块控制和警监测的重要性,特别是在延迟植入植入物放置后的早期阶段.
- 植入物放置的时间可以影响最初的口腔微生物群,可能会影响植入周围的健康结果.
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