社会经济因素与减肥的塞马格卢提德使用之间的关联:丹麦基于人口的横截面研究
Rasmus Bo Hasselbalch1,2, Mille Kyhn Andrea3, Carl Villaro Nolsøe4
1Department of Cardiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
The Lancet regional health. Europe
|February 2, 2026
概括
像Semaglutide这样的葡萄糖类-1激动剂对肥胖有效,但成本是一个障碍. 这项研究发现,更高的收入与增加的减肥类黄胺使用相关,这表明低收入群体的治疗不足.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
背景情况:
- 葡萄糖类-1 (GLP-1) 激动剂,如塞马格卢提德,被认为是治疗肥胖的有效药物治疗方法.
- 与这些药物相关的高成本为许多人提供了潜在的经济障碍.
- 现有的健康差异可能会因获得有效肥胖治疗的不平等机会而加剧.
研究的目的:
- 调查社会经济地位,特别是家庭收入与用于体重管理的塞马格卢提德的使用之间的联系.
- 为了确定收入水平是否影响没有糖尿病的成年人中塞马格卢提德的处方率.
主要方法:
- 一项全国性的,基于登记的,横截面研究使用了丹麦没有糖尿病诊断的成年人的数据进行.
- 对家庭收入进行了调整,以家庭规模进行调整,并分为四分位数,并分析了对塞马格卢提德处方赎回的情况.
- 肥胖被定义为体重指数>30公斤/平方米,人体测量数据来源于哥本哈根总人口研究 (2014-2019).
主要成果:
- 总共有4,531,146名成年人被纳入分析.
- 随着收入四分位数的提高,塞马格卢提德处方率逐渐增加,从最低的1.3%到最高的3.6%.
- 相反,较低收入四分位数 (26%) 的肥胖患病率高于最高收入四分位数 (13%),而在2023年,特别是在高收入女性中,塞马格卢提德的使用量显著增加.
结论:
- 对于减肥的塞马格卢提德的使用与更高的收入水平有积极的关联.
- 这些发现表明,经济因素有助于低收入人群中肥胖的治疗不足.
- 获得有效肥胖治疗的这种差异可能会扩大现有的健康不平等.
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