周围和中央听力功能障碍,心脏代谢多病症和社区老年人的认知表现:一个横截面研究
Jian Ruan1, Xiuhua Hu2, Min Zhang2
1Department of Otorhinolaryngology Head and Neck Surgery, Huadong Hospital Affiliated with Fudan University, Shanghai, China.
Frontiers in neuroscience
|February 2, 2026
概括
心脏代谢多病症 (CMM) 和听力损失,特别是高频听力损失 (HPTA),与老年人的认知能力下降有关. CMM可能会调解HPTA对认知功能的影响,这表明结合干预是有益的.
科学领域:
- 老年学和认知神经科学
- 心脏病学和听力学.
背景情况:
- 与年龄相关的听力损失和心脏代谢多病症 (CMM) 在老年人中很普遍,并且与认知障碍独立相关.
- 心脏代谢性疾病是与年龄相关的听力损失的已知的风险因素,这表明这些疾病之间可能存在潜在的相互作用.
研究的目的:
- 检查CMM和各种类型的听力损失 (低频/高频,中央听力处理功能障碍) 对认知功能的独立和联合影响.
- 研究CMM在与年龄相关的听力损失和认知表现之间的关系中的潜在调解作用.
主要方法:
- 一项涉及508名社区居民,没有痴呆症的老年人的横截面研究.
- 通过SNR评估低频 (LPTA) 和高频听力损失 (HPTA),通过SNR评估中央听力处理功能障碍 (CAPD),并进行全面的神经心理测试.
- 统计分析包括对独立和联合效应进行调整后勤回归,并使用R包"调解"进行调解分析.
主要成果:
- CMM显示了与全球认知表现和执行功能的独立关联.
- 中央听觉处理功能障碍 (CAPD) 与全球认知有关,而高频听力损失 (HPTA) 与注意力/执行功能有关.
- 观察到CMM和HPTA对执行功能的显著联合影响,CMM调解了HPTA对全球认知的影响的16.17%.
结论:
- 在老年人中,CMM和CAPD与全球认知功能有显著的关联.
- CMM和HPTA在执行功能上表现出联合作用,CMM可能会调解HPTA对认知表现的影响.
- 针对长 (与年龄相关的听力损失) 和CMM的综合干预措施可能对延缓认知衰退至关重要.
相关概念视频
01:50Cross-Sectional Research
12.5K
In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...
12.5K
01:24Finding Volume Using Cross-Sectional Area
68
For solids whose cross-sectional areas vary in a predictable way, volume can be determined by integrating these areas along an axis perpendicular to the slices. This approach is particularly useful for polyhedral solids, where classical geometric formulas may not be immediately applicable. A tetrahedron provides a clear example of how cross-sectional integration can be applied to a three-dimensional object with continuously changing geometry.Consider a tetrahedron with height h and a base that...
68
01:26Profile Leveling and Cross Sections
1.6K
Profile leveling and cross-sections are surveying methods used to determine and document terrain elevations for infrastructure projects such as highways, railroads, canals, and pipelines. These methods provide data for earthwork planning and alignment of proposed routes. Profile leveling involves measuring elevations along a fixed line to create a vertical terrain profile. A surveyor sets up a leveling instrument at the benchmark (BM) and records a backsight (BS) to determine the...
1.6K
01:16Spinal Cord: Cross-sectional Anatomy
4.8K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
Gray Matter and its Components
Central to the gray matter is...
4.8K
00:30What are Populations and Communities?
37.8K
Overview
37.8K
01:09Peripherally and Centrally Acting Muscle Relaxants: A Comparison
4.5K
Skeletal muscle relaxants can target the central nervous system [CNS] to reduce muscle tension or act directly at the neuromuscular junction to induce temporary paralysis. These two classes of muscle relaxants are called centrally acting muscle relaxants and peripherally acting muscle relaxants. They differ in their action, mechanism, administration route, and clinical uses.
Centrally acting muscle relaxants can be further divided into spasmolytic and antispasmodic drugs. Spasmolytic...
Centrally acting muscle relaxants can be further divided into spasmolytic and antispasmodic drugs. Spasmolytic...
4.5K