在良性甲状腺结节中比较两种切除方法:射频切除和未冷却的微波切除
Emre Karacay1, Ibrahim Ilker Oz2, Omer Aydiner3
1Department of Radiology, Susurluk State Hospital, Ministry of Health, Balıkesır, Turkey.
非冷却微波切除 (MWA) 与射频切除 (RFA) 相比,为良性甲状腺结节提供了优越的体积减少. 这两种治疗方法都有效,没有观察到并发症,因此需要进一步调查.
科学领域:
- 内分泌学 在内分泌学.
- 最少侵入性手术的方法
- 在瘤学瘤学.
背景情况:
- 良性甲状腺结节很常见,通常需要治疗以缓解症状或化品问题.
- 射频除 (RFA) 是一种成熟的治疗方法,但正在探索新的技术.
- 微波除 (MWA) 是甲状腺结节管理的潜在替代方案.
研究的目的:
- 为了比较非冷却微波除 (MWA) 系统与放射频除 (RFA) 系统对良性甲状腺结节的有效性和并发症率.
- 在多次随访间隔评估结节体积减少和治疗结果.
主要方法:
- 一项前性研究包括56名患有良性甲状腺结节的患者 (62个结节),通过细针吸收活检确认.
- 结节在局部麻醉下使用超声波引导的非冷却MWA或RFA进行治疗.
- 结节体积,直径和回声效应在手术前和后被评估,随访时间为3,6个月和12个月.
主要成果:
- 与RFA相比,未冷却的MWA在3,6和12个月内显示出明显更大的体积减少 (分别P=0.022,P=0.002,P<0.001).
- 在所有随访点 (P<0.001) 上,MWA和RFA都实现了显著的结节体积减少 (P<0.001).
- 在任何治疗组中都没有观察到任何过程性并发症.
结论:
- 与RFA相比,非冷却的MWA系统在减少良性甲状腺结节体积方面表现出更高的有效性.
- MWA和RFA都是安全有效的治疗选择,过程时间相似,并没有观察到并发症.
- 建议进行更大的队列研究来验证这些发现,并进一步确定MWA在甲状腺结节治疗中的作用.
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