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Updated: Feb 4, 2026

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新生儿脑病变的持续不平等:一个30年的全球负担分析 (1990-2021年)
Yiming Yuan1, Mingyue Zhao2,3, Jincao Zhi2,3
1Hunan University of Medicine, Huaihua, Hunan, China.
Frontiers in pediatrics
|February 2, 2026
概括
全球新生儿脑病变 (NE) 负担有所降低,但显著的差异仍然存在,特别是在资源较低的地区. 有针对性的干预措施对于解决这些不平等问题和改善儿童健康结果至关重要.
科学领域:
- 全球健康 全球健康
- 儿科 儿科 儿科
- 流行病学 流行病学
背景情况:
- 新生儿脑病变 (NE) 是全球幼儿死亡和残疾的主要原因.
- 全球存在NE发病率和结果的显著差异,尽管有可用的干预措施.
研究的目的:
- 识别和分析全球NE负担中的不平等现象.
- 为促进 NE 影响儿童健康平等和福祉的战略提供信息.
主要方法:
- 利用了2021年全球疾病负担研究 (GBD) 的数据.
- 在204个国家从1990年到2021年分析了NE发病率,死亡率和残疾调整寿命年 (DALYs).
- 根据年龄,性别,地区和社会人口统计指数 (SDI) 评估数据,使用估计年度百分比变化 (EAPC) 量化趋势.
主要成果:
- 全球NE发病率,死亡率和DALY在1990年至2021年期间下降.
- 男人经历了更高的NE负担.
- 观察到一个明显的差异,低SDI地区的死亡率是高SDI地区的22倍;西撒哈拉以南非洲和南亚承担了最大的负担.
- 低出生体重是全球58.4%的NE DALY的原因,在低和中等SDI地区的影响更大.
结论:
- 尽管全球减排,但新能源负担仍然集中在资源有限的环境中.
- 在低和中等SDI地区,迫切需要有针对性的干预措施,以解决围产期护理和卫生基础设施的不平等问题.
- 中等到高SDI的国家必须适应不断变化的流行病学模式,公平的康复资源对于长期结果至关重要.
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