尿动力学特征在儿童下尿路症状和伴随性ADHD:一个回顾性匹配的病例对照研究
Ping Bai1,2, Lili Liu1,2, Diyi Luo1,2
1Department of Pediatric Urinary Disease Center Nursing, West China Second University Hospital, Sichuan University, Chengdu, China.
Frontiers in pediatrics
|February 2, 2026
概括
患有注意力缺陷/多动症障碍 (ADHD) 的儿童表现出严重的膀问题,包括膀容量减少和增强的疏导器过度活动 (DO). 这些发现突显了ADHD和儿科下泌尿道症状 (LUTS) 之间的联系.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 神经发育障碍 神经发育障碍
- 尿动力学 尿动力学
背景情况:
- 下尿道症状 (LUTS) 在儿童中很常见,影响生活质量.
- 注意缺陷/多动障碍 (ADHD) 与儿童LUTS风险增加有关.
- 关于儿童LUTS中ADHD和泌尿动力学特征之间的关系的研究有限.
研究的目的:
- 评估患有LUTS的儿童中ADHD和尿动力学特征之间的关联.
- 为了比较患有ADHD和没有ADHD的儿童之间的泌尿动力学参数.
主要方法:
- 对144名患有LUTS (36名患有多动症) 的儿童进行了回顾性病例对照研究.
- 标准化泌尿动力学测试,包括膀容量,排毒器压力和排毒器过度活动 (DO) 评估.
- 多变量回归分析以确定尿动力学异常的独立预测因子.
主要成果:
- 与对照组相比,患有ADHD的儿童在第一次冲动,强烈冲动和最大囊泡计容量时,膀体积显著减少.
- 患有ADHD的组在最大填充时显示出显著更高的体压力,并且DO的患病率更高.
- 检测器过度活跃 (DO) 被确定为ADHD儿童尿动力学异常的独立预测因子.
结论:
- 患有多动症的儿童表现出明显的功能性膀异常,包括减少容量和增加体压力和活动.
- 神经行为机制可能是ADHD对膀功能影响的基础.
- 研究结果表明,早期查和干预LUTS在ADHD儿童中的重要性.
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