在慢性肝病中评估萨科佩尼亚诊断工具的评估:一个横截面的观察性研究
Venkata Koti Reddy Chennapareddy1, Shanmughanathan Subramanyam1, A K Koushik1
1Department of Medical Gastroenterology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus
|February 2, 2026
概括
麻症影响48%的肝硬化患者. 这项研究确定了手握强度和肝脏脆弱指数的最佳诊断截止值,推印度特有的值来准确评估这一群体的肉类症.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 老年病的医生 老年病的医生
- 临床营养学 临床营养学
背景情况:
- 萨科佩尼亚是慢性肝病,特别是肝硬化病中不良结果和死亡率的重要预测因素.
- 关于印度肝硬化患者的萨尔科佩尼亚评估工具的数据有限.
研究的目的:
- 为了评估和建立最佳的诊断工具,在第三级护理环境中,在肝硬化患者中诊断萨尔科佩尼亚.
- 通过使用psoas肌肉指数 (PMI),手握强度 (HGS) 和肝脏脆弱指数 (LFI) 来确定萨尔科佩尼亚评估的研究特定切断值.
主要方法:
- 一项涉及50名肝硬化患者的横截面观察性研究.
- 通过CT扫描测量Psoas肌肉指数 (PMI);评估手握强度 (HGS) 和肝脏脆弱指数 (LFI).
- 用于确定HGS和LFI的最佳切断值的接收器操作特征 (ROC) 分析.
主要成果:
- 在研究队列中,肉类的患病率为48%.
- 在较低的PMI和肉症之间发现了显著的关联.
- 在ROC分析中,确定了最佳的HGS切线 (女性17.3公斤,男性26.1公斤) 和高灵敏度和特异性的LFI切线 (4.2).
结论:
- 这项研究强调了印度肝硬化患者中高发性肉症 (48%).
- 针对HGS和LFI的推印度特异性切割值,以准确诊断肉类症.
- 强调需要使用局部切断,以避免高估与西方标准相比.
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