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在手术前检查中的光学连贯性断层扫描和垂体腺瘤的视觉结果
Mateus Dal Fabbro1, Frederico Castelo Moura2, Camila Atihe2
1Division of Neurosurgery, Department of Neurology, University of Campinas, Campinas, Brazil.
Surgical neurology international
|February 2, 2026
概括
下垂体宏瘤手术改善了视力,但光学连贯断层扫描 (OCT) 视网膜测量仍然稳定. OCT可以检测光神经损伤,但视觉周边测量对于早期检测这些瘤导致的视力损失更好.
科学领域:
- 神经眼科神经眼科
- 内分泌学 在内分泌学.
- 神经外科 神经外科
背景情况:
- 垂体腺瘤可以通过压缩视神经引起视力损失.
- 预测手术后的视觉结果仍然具有挑战性.
- 光学连贯断层扫描 (OCT) 可以评估视觉神经病变的严重程度.
研究的目的:
- 评估OCT的预后价值,以预测脑垂体宏腺瘤切除后的视觉恢复.
- 为了比较OCT发现与视觉周边测量 (VP) 结果.
主要方法:
- 对30名患者进行前性研究,这些患者接受了 pituitary macroadenomas 的内内透膜切除术 (EETR).
- 术前和术后的VP和OCT评估在30天和120天.
- 周状视网膜神经纤维层 (RNFL) 和斑点厚度的分析.
主要成果:
- 手术后显著改善视觉周长度.
- 视网膜神经纤维层和黄斑厚度基本保持不变.
- 手术前的RNFL异常与视野缺陷相关.
结论:
- 手术后视力恢复与OCT.测量的视网膜神经元层的变化没有直接联系.
- OCT有效检测压缩性视神经病变.
- 视觉周长度,而不是RNFL厚度,对于早期检测视觉损害更有价值.
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