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Updated: Feb 4, 2026

Modeling Myotonic Dystrophy 1 in C2C12 Myoblast Cells
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平面细胞极性蛋白Vangl2与M-cadherin相互作用,并在小鼠C2C12细胞核细胞中稳定其细胞表面表达

Tadahiro Nagaoka1, Erina Sasaki1, Sakiho Takagi1

  • 1Division for Therapies against Intractable Diseases, Center for Medical Science, Fujita Health University, Toyoake, Japan.

Frontiers in cell and developmental biology
|February 2, 2026
PubMed
概括

平面细胞极性蛋白 Vangl2 在细胞表面稳定M-cadherin,促进肌肉干细胞分化和骨肌肉再生. 这种相互作用对于维持肌肉健康至关重要.

关键词:
这就是M-cadherin.在Vangl2上,你会看到Vangl2.细胞粘附 细胞粘附肌肉发育 (myogenesis) 是一个过程.平面细胞的极性是平面的.这是骨肌肉的骨架肌肉.

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