超声波透明的神经接口用于多模式交互
Raphael Panskus1,2, Andrada Iulia Velea1,2, Lukas Holzapfel2
1Department of Microelectronics, Faculty of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands.
概括
研究人员开发了灵活的,超声透明的神经接口,与功能超声成像 (fUSI) 兼容. 这一突破使同时进行大脑监测和干预成为可能,进步了神经科学和神经技术.
科学领域:
- 神经科学是一个神经科学.
- 生物技术是生物技术.
- 医疗器械 医疗器械
背景情况:
- 神经接口对神经科学和神经技术至关重要.
- 功能性超声波成像 (fUSI) 提供高分辨率的大脑监测.
- 由于超声阻抗,现有的微电极阻碍了FUSI兼容性.
研究的目的:
- 创建灵活的神经接口,透明到超声波.
- 为了实现诊断和治疗功能的无整合.
- 推进用于研究和临床应用的多式联络神经接口.
主要方法:
- 开发了一个理论和模拟框架来评估聚合物和金属的声学透明度.
- 在软神经接口中最大限度地提高超声波传输的设计指南.
- 经过实验验证的声学透明度使用沉浸试验,幻影研究和体内融合.
主要成果:
- 证明了具有高声透明度的灵活神经接口.
- 验证了拟议的设计准则的有效性.
- 在幻影和体内环境中与功能性超声波成像 (fUSI) 确认兼容.
结论:
- 建立了多模式神经接口的基础,将诊断和治疗结合起来.
- 为加强神经技术的科学发现和翻译影响铺平了道路.
- 突出了扩展到治疗性聚焦超声波 (FUS) 的潜力.
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