化疗引起的胃肠粘膜炎后的腹腔综合征:一个病例报告
Tian-le Li1,2, Meng Li2,3, Xiao-Ming Yang2,4
1Heart Center, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China.
Frontiers in medicine
|February 2, 2026
概括
腹腔综合征 (ACS) 是一种罕见但危及生命的化学疗法诱导的膜炎并发症在瘤学患者. 早期识别和积极管理对于这些高风险个体的生存至关重要.
科学领域:
- 在瘤学瘤学.
- 关键护理医学 关键护理医学
- 胃肠病学 胃肠病学
背景情况:
- 腹腔综合征 (ACS) 是一种严重的疾病,通常与创伤或手术有关.
- 在瘤病患者中,ACS异常罕见,特别是作为化疗诱导的胃肠粘膜炎的并发症.
- 这一案例突出了肺癌患者在化疗后出现ACS的独特案例.
研究的目的:
- 在瘤病患者中呈现罕见的ACS病例.
- 描述化学疗法诱导的粘膜损伤到ACS的途径.
- 强调早期识别和管理ACS在免疫受损患者的重要性.
主要方法:
- 一个64岁的男性肺癌患者的病例报告.
- 详细的临床表现,实验室发现和成像结果.
- 重症监护室的管理包括机械通风,血管压缩器,RRT和胃肠道减压.
- 腹内压力 (IAP) 监测和血液动力学优化 (PiCCO指导).
主要成果:
- 患者在化疗后发展出严重的ACS (IAP 28 mmHg) 与败血症休克和多器官衰竭.
- 确定了带有ESBL产生大肠杆菌菌的细菌病.
- 多学科的管理导致了逐渐的改善,第17天的输出管,第19天的重症监护室出院.
结论:
- 化疗诱导的粘膜损伤可以通过肠道性败血症和全身炎症导致ACS.
- 持续的IAP监测和及时的,积极的支持性护理对于生存至关重要.
- 临床医生必须在免疫功能低下的瘤患者中保持对ACS的高度怀疑,这些患者有腹部症状和败血症.
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