93岁男性乳腺恶性外围神经膜瘤:病例报告
Badria Eid Aljohani1, Duaa Salem Alkhayat2, Rouz Faisal Abu Sulami3
1Consultant Breast Oncology Surgery, Breast Center of Excellence, King Salman Bin Abdulaziz Medical City, Medina, Saudi Arabia.
恶性外周神经膜瘤 (MPNSTs) 是一种罕见的乳腺癌. 本案例研究详细介绍了一个老年男性的大型,激进的乳腺MPNST,强调其罕见性和不良预后.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 手术瘤学手术瘤学
背景情况:
- 乳腺瘤很罕见,占乳腺恶性瘤的不到1%.
- 恶性外围神经膜瘤 (MPNSTs) 是源自外围神经的侵袭性软组织瘤.
- 乳腺MPNST异常罕见,这是第四个报告的男性患者病例.
研究的目的:
- 报告一个极其罕见的恶性周围神经膜瘤 (MPNST) 的男性患者的乳房病例.
- 描述乳腺MPNST的临床表现,病学发现和结果.
- 为了对男性乳腺MPNST的有限文献做出贡献.
主要方法:
- 一个93岁的男性患有巨大的,疼痛的右乳腺质量.
- 临床检查显示了一个不动的,的和的质量.
- 组织病理学评估和免疫组织化学 (vimentin,S100,p63) 用于诊断.
- 通过右乳房切除术进行手术管理.
主要成果:
- 一个20x30厘米不动的,功能性的,发的右乳腺质量被确定.
- 组织病理学证实了一种高等级的状细胞肉瘤,通过免疫组织化学诊断为MPNST.
- 患者通过乳腺切除术成功进行了手术清除.
- 患者在手术后三个月发生了转移性疾病 (肺转移与恶性多叶流液).
结论:
- 乳腺MPNST是一种极其罕见和激进的恶性瘤,特别是在男性中.
- 早期诊断和手术干预至关重要,但可能无法预防疾病的侵袭性进展.
- 这一案例强调了与老年男性中先进乳腺MPNST相关的罕见性和不良预后.
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