老年COVID-19幸存者的精神障碍和营养不良风险:一项观察性研究
Ria Maria Theresa1, Marlina Dewiastuti2, Sri Rahayu Ningsih3
1Psychiatry, Universitas Pembangunan Nasional Veteran Jakarta, Jakarta, DKI, 12310, Indonesia.
F1000Research
|February 2, 2026
概括
老年COVID-19幸存者面临精神障碍和营养不良的风险增加,风险随着年龄和严重症状的增加而升级. 这项研究强调了针对感染后的老年护理的需要.
科学领域:
- 老年医学 老年医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- COVID-19影响11-15%的老年人,病例死亡率为8.9%,随着年龄的增长而上升.
- COVID-19幸存者,特别是老年人,表现出精神健康障碍和营养不良的风险较高.
- 感染后的炎症状态可能导致超级catabolism,影响神经内分泌功能和蛋白质代谢,导致脆弱性.
研究的目的:
- 评估与老年COVID-19幸存者的精神障碍相关的患病率和风险因素.
- 评估老年COVID-19幸存者中营养不良的发生率和贡献因素.
主要方法:
- 一项涉及100名德波克老年参与者的横截面研究,持续两个月.
- 数据收集包括直接的人类测量和标准化问卷:精神障碍的SRQ-20和营养不良的MNA.
- 分析确定了年龄,疾病严重程度和并发症作为潜在的风险因素.
主要成果:
- 70岁以上的年龄,严重的COVID-19症状和多重并发症是精神疾病的重要风险因素.
- 年龄较大 (70岁以上),中度COVID-19症状和多重并发症被确定为营养不良的关键风险因素.
- 根据这些因素,赔率比率表明这两种条件的风险大幅增加.
结论:
- 在老年人中,COVID-19感染显著增加了精神障碍和营养不良的风险.
- 这些疾病的风险在老年人和患有更严重疾病或多种并发症的人群中增加.
- 研究结果强调了监测和干预老年COVID-19幸存者的心理健康和营养状况的重要性.
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