HD-tDCS通过前额叶皮层缓解失眠的抑制控制和睡眠问题,具有客观的短睡眠时间
Haobo Zhang1, Zhangwei Lv2,3, Zijie Tang2,3
1School of Psychology, Northwest Normal University, Lanzhou, 730070, China.
International journal of clinical and health psychology : IJCHP
|February 2, 2026
概括
针对右脊侧前额皮质 (dlPFC) 的高清度横直流刺激 (HD-tDCS) 改善了对客观短睡眠时间 (ISSD) 失眠障碍的抑制控制和睡眠质量. 这种神经调节方法为ISSD患者提供了安全有效的治疗选择.
科学领域:
- 神经科学是一个神经科学.
- 睡眠医学 睡眠医学
- 神经调节是一种神经调节.
背景情况:
- 客观睡眠时间短的失眠障碍 (ISSD) 是一种严重的疾病,与严重的健康风险有关.
- 改善抑制控制 (IC) 在缓解ISSD的睡眠问题方面显示出希望.
- 需要针对IC的有效干预措施来管理ISSD症状.
研究的目的:
- 为了研究高清度跨直流刺激 (HD-tDCS) 在右背侧前额皮层 (dlPFC) 的疗效.
- 评估HD-tDCS对ISSD患者抑制控制和睡眠质量的影响.
主要方法:
- 一个随机,单盲,假控制试验,涉及50名ISSD参与者.
- 参与者接受了真实或假的HD-tDCS (2mA,25分钟/天7天).
- 主要结局包括抑制控制 (NoGo-ACC) 和主观睡眠质量 (PSQI,ISI);次要结局是客观睡眠措施.
主要成果:
- 与假药相比,HD-tDCS显著改善了响应抑制 (NoGo-ACC).
- 接受HD-tDCS治疗的参与者表现出更好的主观睡眠质量 (ISI,PSQI) 和睡眠延迟.
- 在PSQI的白天功能子维度中,在HD-tDCS组中也显示出显著的改善.
结论:
- 正确的dlPFC向的HD-tDCS是一种潜在的安全和有效的神经调节治疗ISSD.
- 优化方案可能是必要的,以实现ISSD的完全临床缓解.
- 未来的研究应该探索联合干预和神经化学评估,以了解潜在的机制.
相关概念视频
Insufficient Sleep and Sleep Deprivation
939
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
939
Stages of Sleep
1.4K
Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
1.4K
Understanding Sleep
1.6K
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
1.6K
Sleep Apnea
567
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
567
Sleepwalking and Sleep Talking
1.0K
Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
1.0K
Substance Use Disorders Affecting Sleep
449
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
449


