由于Candida不显而易见的无症状疹在患有血液恶性病的患者
Andrés Soto1,2, Javier Tinoco-Cahuana1, Paulo Charpentier-Videla1
1Fundación Arturo López Pérez OECI Cancer Center, Unit of Infectology, Santiago, Chile, falp.cl.
Case reports in infectious diseases
|February 2, 2026
概括
这项案例研究突出显示,在白血病患者中,无症状的尿路感染是由可纳耐药的Candida inconspicua引起的. 它强调对罕见的酵母菌感染进行仔细的诊断和抗菌药物管理.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
背景情况:
- 隐形菌是一种机会性酵母,越来越多地在免疫受损的个体中被发现.
- 无症状 kandiduria 呈现出诊断挑战,特别是在耐药菌株.
研究的目的:
- 报告一个由可纳耐药Candida inconspicua引起的无症状尿病例.
- 讨论免疫受损患者罕见的,耐药的Candida感染的临床影响和管理.
主要方法:
- 一个43岁的B细胞急性淋巴细胞白血病患者接受化疗的病例报告.
- 使用MALDI-TOF识别Candida不显眼的MS.
- 抗真菌敏感性测试,包括可纳最小抑制度 (MIC).
主要成果:
- 在发烧性中性质衰竭期间,从尿液培养物中反复分离出Candida inconspicua.
- 已证明具有较高的可纳耐药性 (MIC:16.0μg/mL).
- 无症状呈现,发烧通过抗菌治疗消失,没有抗真菌治疗.
结论:
- 与耐药性Candida inconspicua结合的无症状尿症构成了临床困境,需要精确的鉴定.
- 抗菌药物管理和仔细的风险效益评估对于抗真菌治疗决策至关重要.
- 由于耐药性和生物膜潜力,Candida inconspicua的出现需要在血液瘤患者中保持警.
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