转录基因组学揭示了与料效率相关的肠微生物群的饮食驱动的结构,生态和功能适应
Limei Lin1, André L A Neves2, Kim H Ominski3
1Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC, Canada.
ISME communications
|February 2, 2026
概括
高料效率的牛放大了有益的小肠微生物,提高了营养利用率. 这种宿主介导的微生物放大改善了料转化,为反动物生产提供了可持续的解决方案.
科学领域:
- 鲁门微生物群生态学
- 动物料效率的提升 动物料效率
- 转基因组学和宿主微生物相互作用
背景情况:
- 肠微生物组对于反动物的料效率至关重要.
- 关联微生物适应,饮食和宿主料效率的机制尚不清楚.
- 了解这些相互作用是提高反动物生产可持续性的关键.
研究的目的:
- 为了研究与宿主料效率相关的,调控皮微生物群落的生态机制.
- 为了确定与高与低料效率相关的微生物血统和功能适应.
- 探索宿主微生物相互作用在调节牛的料转化中的作用.
主要方法:
- 分析了120个具有高或低料效率的安格斯公牛的metatranscriptomic数据集.
- 使用中立社区模型分析和碳水化合物活性酶分析.
- 在不同饮食 (料与谷物) 中比较微生物社区结构和功能能力.
主要成果:
- 随机过程在很大程度上控制了高和低料效率群体中的小 rumen 微生物社区结构.
- 高养效率的公牛对特定的适应饮食的微生物系 (例如,Fibrobacter,Butyrivibrio,UBA1067) 产生了积极的选择.
- 这些精选的微生物拥有碳水化合物结合模块,增强了基质降解,与具有随机结构和减少专业化的低效率公牛不同.
结论:
- 具有更高料效率的牛促进了与饮食输入功能一致的微生物种群 (高效的宿主介导微生物放大).
- 微生物组的生态组合和功能适应是宿主料效率的关键贡献者.
- 这些发现为基于微生物组的策略提供了基础,以提高反动物生产的可持续性.
相关概念视频
Ecological Niches
26.6K
All organisms have a position within an ecosystem. The complete set of living and nonliving factors—including food resources, climate, and terrain—that define the position of a given organism are collectively referred to as the organism’s ecological niche.
26.6K
Ecological Disturbance
21.1K
An ecological disturbance is a temporary disruption in the environment resulting from abiotic, biotic, or anthropogenic factors, causing a pronounced change in an ecosystem. The impact of an ecological disturbance, which can depend on its intensity, frequency, and spatial distribution, plays a significant role in shaping the species diversity within the ecosystem.
21.1K
Ecological Succession
21.5K
Ecological succession is influenced by the processes of facilitation, inhibition, and toleration. Facilitation occurs when early successional species create more favorable ecological conditions for subsequent species, such as enhanced nutrient, water, or light availability. In contrast, inhibition happens when early successional species create unfavorable ecological conditions for potential successive species, such as limiting resource availability. In some cases, later successional species...
21.5K
Structural Protein Function
30.0K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to...
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to...
30.0K
Structural Protein Function
3.3K
3.3K
Covalently Linked Protein Regulators
9.6K
Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein....
These groups modify specific amino acids in a protein....
9.6K


