绘制双极障碍的全球负担和不平等,1990-2021年,并对2050年进行预测:系统分析
Saboor Saeed1,2,3, Zeyu Luo4, Huaizhi Wang5
1Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Bipolar disorders
|February 2, 2026
概括
双相情感障碍负担的全球不平等仍然存在,不成比例地影响女性和高收入地区. 预测表明负担越来越重,性别差距在发病率上越来越小,需要有针对性的干预措施.
科学领域:
- 全球心理健康全球心理健康
- 流行病学 流行病学
- 健康差异 在健康上的差异
背景情况:
- 双极性障碍 (BD) 对全球健康产生重大影响,影响数百万人,需要有效的公共卫生政策.
- 了解 BD 负担的分布和趋势对于资源分配和干预策略至关重要.
研究的目的:
- 评估全球在双相情感障碍负担上的不平等.
- 预测双相情感障碍负担的未来轨迹到2050年.
主要方法:
- 全球疾病负担分析2021年204个国家和地区的数据.
- 按年龄,性别和社会人口指数 (SDI) 五分位数进行分层.
- 计算年龄标准化患病率,发病率和残疾生活年数 (YLDs);使用SII和CI进行不平等评估;使用ARIMA模型进行趋势预测.
主要成果:
- 从1990年到2021年,全球BD发病率增加,而患病率和YLDs保持稳定.
- 女人始终表现出比男性更高的患病率;高SDI地区,特别是澳大利亚,报告的最高率.
- 绝对不平等的发病率增加,而相对不平等的发病率减少;预测显示全球负担不断增加,性别发病率趋同.
结论:
- 在双相情感障碍负担方面,持续的全球不平等不成比例地影响女性和高SDI地区.
- 预计的趋势表明,病发率负担越来越大,性别差距越来越小.
- 有针对性的干预措施和进一步研究长期影响,包括COVID-19影响,至关重要.
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