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A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
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在阿波利波蛋白E基因多态和血清脂质指标与阿尔茨海默病风险之间存在关联

Honghai Chen1, Huiming Zhang2, Miaomiao Yang3

  • 1Department of Molecular Biology Laboratory, Shenyang Fifth People's Hospital, Shenyang, Liaoning, China.

Journal of Alzheimer's disease : JAD
|February 2, 2026
PubMed
概括

阿波利波蛋白E4 (APOE4) 基因型,加上总胆固醇和LDL胆固醇升高,与阿尔茨海默氏症 (AD) 发病有很强的相关性. 这种组合可以作为AD诊断和治疗的有价值的辅助生物标志物.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.阿波利波蛋白 E 基因多态.诊断 诊断 诊断 诊断 诊断 诊断血清学指标 血清学指标

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