将随机对照试验的搜索过器与Covidence的Cochrane RCT分类器相结合:一种方法验证研究
1https://ror.org/04507cg26Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU), Stockholm, Sweden.
Research synthesis methods
|February 2, 2026
概括
柯克伦RCT分类器为识别随机对照试验 (RCT) 提供了更高的回忆力,但增加了读取 (NNR) 所需的数量. 将其与现有的搜索过器相结合,可以优化结果,平衡回忆和工作负载.
科学领域:
- 信息科学 信息科学 信息科学
- 卫生技术评估 卫生技术评估
- 医疗信息学 医疗信息学
背景情况:
- 系统性审查依赖于准确识别随机对照试验 (RCT).
- 建立了对Ovid MEDLINE和Embase.com等数据库的搜索过器,有助于RCT检索.
- 柯克伦RCT分类器是用于在文献搜索中识别RCT的新工具.
研究的目的:
- 将Cochrane RCT分类器的回忆和读取所需数 (NNR) 与已有的搜索过器进行比较.
- 评估Cochrane RCT分类器单独和与现有过器相结合的性能.
- 评估这些工具对搜索结果和卫生技术评估工作量的影响.
主要方法:
- 一套1103个RCT的黄金标准被选中用于绩效评估.
- 在Cochrane RCT分类器 (Covidence),Ovid MEDLINE波器和Embase波器中计算了回忆和NNR.
- 使用卫生技术评估报告的三个案例研究验证了这些工具对搜索结果和NNR的影响.
主要成果:
- 科克兰RCT分类器显示了最高的召回率 (99.64%),其次是Ovid MEDLINE (98.73%) 和Embase (98.46%) 过器.
- 与单独使用的过器相比,Cochrane RCT分类器的结果是更高的NNR.
- 将Cochrane RCT分类器与现有过器相结合,可以减少NNR,同时保持高回忆率 (Ovid: 98.46%,Embase: 98.28%).
结论:
- 科克兰RCT分类器在回忆方面表现出色,但增加了无关记录的数量,可能增加选工作量.
- 单独使用Cochrane RCT分类器而不是当前的过器可能会增加工作量.
- 一种混合方法,将Cochrane RCT分类器与已建立的RCT过器相结合,提供了一个实用的解决方案,以平衡高回忆率与可管理的NNR.
相关概念视频
01:17Cochran's Q Test
983
Cochran's Q Test is a nonparametric statistical test used to determine if there are potential differences in the outcomes of three or more related groups on a binary (yes/no) or dichotomous outcome. It is essentially an extension of the McNemar Test, which is limited to two related samples - Cochran's Q test can handle three or more related samples, making it more versatile in scenarios where subjects are measured under multiple conditions. The test statistic follows a Chi-Square...
983
03:35Classifying Matter by Composition
90.4K
Matter: Pure Substances and Mixtures
According to its composition, the matter can be classified into two broad categories — pure substances and mixtures.
A pure substance is a form of matter that has a constant composition throughout with uniform properties. For example, any sample of sucrose has the same composition and same physical properties, such as melting point, color, and sweetness, regardless of the source from which it is isolated.
A mixture is composed of two or...
According to its composition, the matter can be classified into two broad categories — pure substances and mixtures.
A pure substance is a form of matter that has a constant composition throughout with uniform properties. For example, any sample of sucrose has the same composition and same physical properties, such as melting point, color, and sweetness, regardless of the source from which it is isolated.
A mixture is composed of two or...
90.4K
01:20Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs
248
Body:Bioequivalence experimental study designs are crucial methodologies used in evaluating and comparing the bioavailability of different drug products. These designs are categorized into various types: completely randomized, randomized block, repeated measures, cross and carry-over, and Latin square designs.Completely randomized designs involve randomly allocating treatments to all subjects participating in the experiment. This allocation is achieved by assigning unique random numbers to...
248
02:49Classifying Matter by State
103.4K
Chemistry is the study of matter and the changes it undergoes. Matter is anything that has mass and occupies space. Matter is all around us; the air, water, soil, mountains, even our bodies are all examples of matter. Matter is divided into three states — solid, liquid, and gas — that are commonly found on earth. The fourth state of matter, plasma, occurs naturally in the interiors of stars.
103.4K
01:27Passive Filters
1.0K
Passive filters are utilized to shape the frequency spectrum of signals across a diverse array of applications. These filters, using only passive elements like resistors (R), inductors (L), and capacitors (C), are capable of selectively allowing or blocking certain frequency ranges without the need for external power sources.
Low-Pass Filters
Low-pass filters are designed to transmit signals with frequencies lower than the cutoff frequency, ωc, and attenuate those above it. The cutoff...
Low-Pass Filters
Low-pass filters are designed to transmit signals with frequencies lower than the cutoff frequency, ωc, and attenuate those above it. The cutoff...
1.0K
01:29Reliability and Validity
13.9K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
13.9K