化疗患者药物不良反应的发生:一个横截面研究
Zuha Shyma1, Suha Zulekha1, Sumithra Devadiga1
1Department of Pharmacy Practice, Karavali College of Pharmacy, Mangalore, India.
概括
化疗药物不良反应 (ADR) 是常见的,影响70%的患者,轻度至中度严重. 加强药物监测对于患者安全和治疗结果至关重要.
科学领域:
- 在瘤学瘤学.
- 药物监督 药物监督 药物监督
- 临床药房 临床药房
背景情况:
- 化疗对于癌症治疗至关重要,但受到毒性和报告不足的不良药物反应 (ADR) 的限制.
- 有效的药物监测对于患者安全和优化化疗方案至关重要.
研究的目的:
- 为了确定化学疗法患者的ADR的频率,类型,严重程度和管理.
- 突出在临床实践中强有力的ADR监测的重要性.
主要方法:
- 一项为期12个月的横截面研究,涉及三级医院的327名化疗患者.
- 通过可疑ADR报告表格收集的数据,使用修改后的纳兰乔尺度评估因果关系,使用哈特维格等人评估严重程度. 尺度. 尺度. 这是一个尺度.
主要成果:
- 70%的患者经历了ADR (230/327),报告了372个事件 (每位患者为1.6).
- 常见的不良反应包括血小板缺血,中性质缺血和腹. 卵巢和乳腺癌患者的发病率更高. 大多数不良反应是"可能的"和轻度到中度的严重程度.
结论:
- 警的ADR监测对于减轻并发症和改善化疗结果至关重要.
- 进一步的研究可以根据癌症阶段对针对性干预进行ADR数据的分层.
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