在MACS/WIHS联合队列研究中,与艾滋病毒携带或不携带的男性和女性心血管疾病风险和跌倒
Elizabeth Vásquez1,2, Mark H Kuniholm1, Allison A Appleton1,2
1Department of Epidemiology and Biostatistics, College of Integrated Health Sciences, University at Albany, Albany NY.
Journal of acquired immune deficiency syndromes (1999)
|February 2, 2026
概括
高心血管疾病 (CVD) 风险与男性和女性,尤其是艾滋病毒感染者,跌倒的增加有关. 针对性,性别特定的预防策略对于管理临床实践中的跌倒风险至关重要.
科学领域:
- 老年学是指老年学的学科.
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 心血管疾病 (CVD) 风险是一个重大的健康问题.
- 跌倒是一个常见的问题,特别是在老年人和患有慢性疾病的人群中.
- 心血管疾病风险和跌倒之间的关系,特别是在艾滋病毒感染者群体中,需要进一步调查.
研究的目的:
- 检查心血管疾病 (CVD) 风险和跌倒史之间的横截面关联.
- 调查心血管疾病风险与过去一年中跌倒人数之间的关系.
- 分析这些关联在男性和女性,艾滋病毒和没有艾滋病毒.
主要方法:
- 利用了来自MACS/WIHS联合队列研究 (2020-2022) 的数据,其中包括2,723名参与者.
- 使用聚合队列方程评估了10年心血管疾病风险,并将其分为四个级别.
- 收集自我报告的跌倒数据 (最近跌倒,一次跌倒,多次跌倒) 并使用多项回归分析,按性别分层并调整共变量.
主要成果:
- 在男性中,高心血管疾病风险与最近的一次跌倒 (aOR: 3.12) 和过去一年的一次跌倒 (aOR: 3.66) 有关.
- 在女性中,高心血管疾病风险与过去一年多次跌倒 (aOR:2.06) 有关.
- 这些关联在艾滋病毒感染者和未感染者的男性和女性中都被观察到.
结论:
- 将跌倒风险评估纳入心血管疾病管理是必不可少的.
- 调查结果强调需要针对性,以性别为导向的防摔策略.
- 应特别注意艾滋病毒和高心血管疾病风险的个体.
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