表观遗传重编程驱动着Populus中的年度生长休眠周期
Yue Li1, Xintong Xu2, Kejing Wang1
1Hubei Hongshan Laboratory, Hubei Engineering Technology Research Center for Forestry Information, College of Horticulture and Forestry Sciences, Huazhong Agricultural University, 430070, Wuhan, China.
The Plant cell
|February 2, 2026
概括
树木在冬天通过季节性生长休眠周期生存,这种周期是由芽顶部的表观遗传变化调节的. 这项研究揭示了染色质动态,特别是H3K27me3和PtLHP1,如何控制这种重要的植物适应.
科学领域:
- 植物生物学 植物生物学
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
- 分子生态学分子生态学
背景情况:
- 温带和北极地区的多年生植物依靠季节性生长休眠周期来生存冬季.
- 这个循环是由射击顶部的基因活动控制的,受环境线索和染色质状态的影响.
- 控制树木季节性反应的精确表观遗传机制尚不清楚.
研究的目的:
- 为了描述Populus () 中的染色质动态,在整个年度生长休眠周期中发芽.
- 调查多抑制复合体2 (PRC2) 和Like HETEROCHROMATIN PROTEIN 1 (PtLHP1) 在调节季节性转变中的作用.
- 提供一个全面的树木季节性生长调节的表观遗传景观.
主要方法:
- 在五个关键季节阶段整合了有关染色质可访问性,基因组修饰 (H3K27me3) 和转录组动态的数据.
- 对染色体重编程事件与转录原子变化相关的分析.
- 对混合树中PtLHP1表达的操纵,以评估其对休眠和芽断裂的影响.
主要成果:
- 确定了与转录基因转移相关的特定阶段和近距离染色体重编程事件.
- 证明PRC2对H3K27me3的沉积对于调节生长休眠过渡至关重要.
- 表明操纵PtLHP1会影响休眠释放和芽断裂,其中PtLHP1与H3K27me3区域共定位.
结论:
- 这项研究阐明了控制树木季节性生长和休眠的表观遗传景观.
- 在季节性转变期间,PtLHP1在维持H3K27me3平衡中发挥作用.
- 这些发现为理解和潜在地操纵树木中的现象性可塑性提供了分子目标.
相关概念视频
Epigenetic Regulation
33.8K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
33.8K
Epigenetic Regulation
3.9K
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
X-chromosome...
3.9K
Meristems and Plant Growth
49.5K
Plants grow throughout their lives; this is called indeterminate growth, and it distinguishes plants from most animals. Although certain parts of plants stop growing (e.g., leaves and flowers), others grow continuously—like roots and stems.
49.5K
Lysogenic Cycle of Bacteriophages
67.9K
In contrast to the lytic cycle, phages infecting bacteria via the lysogenic cycle do not immediately kill their host cell. Instead, they combine their genome with the host genome, allowing the bacteria to replicate the phage DNA along with the bacterial genome. The incorporated copy of the phage genome is called the prophage. Some prophages can re-activate and enter the lytic cycle. This often occurs in response to a perturbation, such as DNA damage, but can also transpire in the absence of...
67.9K
The Nitrogen Cycle
60.2K
Nitrogen atoms, present in all proteins and DNA, are recycled between abiotic and biotic components of the ecosystem. However, the primary form of nitrogen on Earth is nitrogen gas, which cannot be used by most animals and plants. Thus, nitrogen gas must first be converted into a usable form by nitrogen-fixing bacteria before it can be cycled through other living organisms. The use of nitrogen-containing fertilizers and animal waste products in human agriculture has greatly influenced the...
60.2K
Energy to Drive Translocation
2.8K
Mitochondrial protein import is powered by two distinct energy sources: ATP hydrolysis and electrochemical potential across the inner membrane. Newly synthesized precursors are bound by cytosolic chaperones of the Hsp70 family, which guide them to the import receptors on the mitochondrial surface. Utilizing the energy of ATP hydrolysis, Hsp70 chaperones transfer these precursors to the TOM receptors on the mitochondrial outer membrane.
Generally, polypeptides are unfolded by two distinct...
Generally, polypeptides are unfolded by two distinct...
2.8K


