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Updated: Feb 4, 2026

Obtaining Human Microglia from Adult Human Brain Tissue
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微质中的Ythdf2损失通过增加微质激活和微血管异常而加剧缺血性视网膜病变

Hong-Jing Zhu1, Yi-Chen Zhang2, Ye-Ran Zhang2

  • 1Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing 210029, China; Department of Ophthalmology, Children's Hospital of Nanjing Medical University, Nanjing 210029, China.

Journal of advanced research
|February 2, 2026
PubMed
概括

微质中YTHDF2的损失会扰乱视网膜血管的发育,并通过影响ACE和BMP4.4来恶化疾病. 这表明向YTHDF2-ACE/BMP4通路可以治疗微血管疾病.

关键词:
微质细胞中的微质细胞微血管功能障碍是什么在N(6) -甲基氨酸 (m(6) A) 修改中.这就是 Ythdf22.

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