在患有败血症的患者中,左心室喷射率升高的预后影响
1Department of Critical Care Medicine, West China Hospital of Sichuan University; chuk282@outlook.com.
Journal of visualized experiments : JoVE
|February 2, 2026
概括
在败血症患者中,高动态左心室喷射分数 (LVEF) 预测死亡率更高. 这一发现突显了重症监护病房内LVEF的预后意义,敦促加强临床警,以改善患者的治疗结果.
科学领域:
- 心脏病学 心脏病学
- 临界护理医学 临界护理医学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 左心室缩功能是败血症的一个有争议的预后标志物.
- 在败血症患者中评估左心室喷射分数 (LVEF) 对于了解死亡风险至关重要.
研究的目的:
- 评估左心室喷射率 (LVEF) 的不同水平与败血症患者的死亡结果之间的关联.
- 确定LVEF是否是重症监护室 (ICU) 败血症患者28天死亡率的显著预测因素.
主要方法:
- 对ICU入院的成年败血症患者进行了回顾性,单中心的纵向队列研究.
- 在ICU入院后七天内进行的跨胸腔心声扫描 (TTE).
- 患者分为高动态 (LVEF ≥70%),正常 (LVEF 55%-70%),抑郁 (LVEF ≤55%) 的LVEF组.
主要成果:
- 在3,363名患者中,高动态LVEF是28天死亡率的最强预测因素.
- 超动态LVEF与正常LVEF相比,独立地与死亡风险增加3.643倍有关.
- 超动态左心室功能与ICU败血症患者28天死亡率升高之间存在显著联系.
结论:
- 超动态左心室功能是进入ICU的败血症患者28天死亡率增加的重要独立预测因素.
- 由于其预后影响,在败血症中提高对高动态LVEF的临床意识是有必要的.
- 这项研究强调了心声回声学评估在败血症患者分层风险中的关键作用.
相关概念视频
Freezing Point Depression and Boiling Point Elevation
40.1K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
40.1K
Elevation of Intermediate Points on Vertical Curves
290
Vertical curves are essential in roadway design because they provide smooth transitions between varying roadway grades. Designing vertical curves involves calculating intermediate elevations and identifying the curve's highest or lowest point, which is essential for optimal roadway performance.Intermediate elevations on a vertical curve are determined using the tangent offset method. This method considers the initial elevation at the start of the curve, the grades, and the curve's geometry. The...
290
Subcellular Fractionation
8.9K
The homogenate obtained after cell lysis contains various membrane-bound organelles that can be further separated into pure fractions by subcellular fractionation. These isolates are used to study specific cellular components, analyze localized protein activity, and are even employed in diagnostics. Fractionation is typically achieved using centrifugation methods, the most common being density-gradient and differential centrifugation.
Differential Centrifugation
Differential centrifugation is...
Differential Centrifugation
Differential centrifugation is...
8.9K
Partial Fractions
220
A partial fraction is a component of a rational expression represented as the sum of simpler fractions. When a rational function is expressed as a ratio of two polynomials, it can often be decomposed into a sum of fractions whose denominators are simpler polynomials, typically linear or irreducible quadratic factors. This process is called partial fraction decomposition, and it is used to simplify complex expressions for integration, solving equations, or analysis.Partial fraction decomposition...
220
Mixtures of Gases: Dalton's Law of Partial Pressures and Mole Fractions
44.1K
Unless individual gases chemically react with each other, the individual gases in a mixture of gases do not affect each other’s pressure. Each gas in a mixture exerts the same pressure that it would exert if it were present alone in the container. The pressure exerted by each individual gas in a mixture is called its partial pressure.
44.1K
Integration of Rational Functions Using Partial Fractions
89
Rational functions are expressions written as the ratio of two polynomials, and their integrals are evaluated by simplifying the integrand into manageable parts. These functions are classified as proper or improper based on the degrees of the numerator and denominator.A rational function is proper when the degree of the numerator is less than the degree of the denominator. In this case, partial fraction decomposition is used to rewrite the function as a sum of simpler rational terms. The...
89


