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Updated: Feb 4, 2026

Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function
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Published on: April 26, 2024

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人类S1PR1基因中有害的非同义SNP的in-silico表征揭示了结构不稳定性和改变的联结体亲和力

Sangram Biswas1, Dipankar Sardar1, Md Arju Hossain2

  • 1Department of Biotechnology, Bangladesh Agricultural University, Mymensingh, Bangladesh.

PloS one
|February 2, 2026
PubMed
概括

这项研究确定了破坏性S1PR1基因变异 (nsSNP),影响受体功能和药物反应. 这些高风险突变可能会影响自身免疫性疾病的易感性和治疗结果.

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