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在中国的MSM中识别艾滋病毒检测和PrEP吸收性行为模式:潜伏类分析
Yannan Li1, Hao Zheng2, Haojie Huang2
1Faculty of Medicine, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
International journal of STD & AIDS
|February 2, 2026
概括
在中国与男性发生性关系的男性 (MSM) 之间,明显的性行为概况突出了艾滋病毒检测和暴露前预防 (PrEP) 需求的多样性. 定制的预防策略和可访问的PrEP提供对于有效的艾滋病毒预防至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 行为科学 行为科学
背景情况:
- 在中国,与男性发生性关系的男性 (MSM) 面临着严重的艾滋病毒风险.
- 低吸收的暴露前预防 (PrEP) 在MSM有助于持续的艾滋病毒传播.
- 了解行为模式是改善MSM艾滋病预防策略的关键.
研究的目的:
- 在中国的HIV阴性/未知MSM中识别明显的性行为特征.
- 检查这些个人资料与艾滋病毒检测行为之间的关联.
- 评估PrEP吸收率,并确定不同行为群体内的PrEP获取障碍.
主要方法:
- 隐性类别分析 (LCA) 用于根据性行为对486名性活跃,HIV阴性/未知MSM进行分类.
- 分析的行为包括没有避孕套的性行为,伴侣数量,群体性行为,商业性行为和性化药物使用.
- 人口统计学,艾滋病毒检测频率和PrEP吸收/障碍物在确定类别中被检查.
主要成果:
- 确定了四个不同的行为类别:"保留" (34%),"选择性" (36%),"安全玩家" (14%) 和"不受约束" (16%).
- "不受约束"的MSM显示性化药物使用和PrEP使用率最高 (27-40%),而"安全玩家"的HIV测试率高 (89%),但PrEP使用率较低.
- 对PrEP的障碍包括成本 (45%),副作用 (41%) 和缺乏知识 (34%);超过82%的人更喜欢直接提供PrEP.
结论:
- MSM之间的行为异质性需要定制的HIV预防策略.
- 可访问的,直接提供PrEP,以及有针对性的教育,可以解决已识别的障碍.
- 将行为洞察整合到PrEP程序中可以提高吸收率和降低艾滋病毒发病率的有效性.
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