早期的心理社会剥夺改变了整个青春期神经动态的精细化
Marta Andujar1, Lucrezia Liuzzi2, Daniel S Pine2
1Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD 20892.
概括
早期的机构护理会扰乱大脑的发育. 与机构同龄人相比,寄养儿童的神经动力学和执行功能有所改善,突出显示了早期环境对认知控制成熟的影响.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 认知科学 认知科学
背景情况:
- 青春期对于大脑发育和执行功能成熟至关重要.
- 在青少年时期的突触修剪精炼神经电路,可能提高认知表现.
- 计算模型预测突触修剪稳定神经动力学.
研究的目的:
- 调查早期机构护理对青少年神经动态的影响.
- 测试有关突触修剪和神经稳定性的计算预测.
- 将改变的神经动态与不同护理历史的儿童的执行功能表现联系起来.
主要方法:
- 利用来自布加勒斯特早期干预项目的脑电图 (EEG) 数据.
- 作为一个线性动态系统,在Flanker任务期间模拟试验对试验EEG残留.
- 在有或没有机构护理史的儿童中,在青春期内追踪了自身值大小的变化.
主要成果:
- 所有群体的自身价值大小随着年龄的增长而下降,这表明神经成熟.
- 具有机构护理历史的儿童表现出更高的固有值,这表明神经动力学改进中断.
- 较高的固有值与Flanker任务的表现较差相关,将神经变化与执行功能缺陷联系起来.
结论:
- 早期的剥夺显著影响神经动态的发育轨迹.
- 机构护理可以导致支持认知控制的大脑系统的持久变化.
- 寄养干预可以减轻早期剥夺对神经和认知发育的负面影响.
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