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主要的体内瘤模仿体内血瘤:一个说明性的案例

Takaaki Ishikawa^1,2, Takao Tsurubuchi^1,3,4, Kumie Nagatomo⁵

¹Department of Neurosurgery, Institute of Medicine, University of Tsukuba, Tennodai, Tsukuba-shi, Ibaraki.

Journal of neurosurgery. Case lessons

|February 2, 2026

概括

儿科的体内瘤很少见,但可以模仿体内血瘤. 增强型MRI显示出突出进入大脑的结节是这些侵袭性内瘤的关键诊断线索.

科学领域:

儿科神经瘤学儿童神经瘤学
神经辐射学神经辐射学
手术神经病理学手术神经病理学

背景情况:

罕见的儿科体内瘤可能表现出类似于体内血液瘤的症状.
儿童体下质量的差异诊断包括淋巴瘤,肉瘤和转移性癌症.

研究的目的:

要突出诊断挑战和临床呈现的儿科患者罕见的原发性亚皮质瘤.
强调高级成像和分子分析在诊断和分类具有挑战性的内瘤中的重要性.

主要方法:

一个3岁男孩的病例报告,有慢性腹腔内血瘤的病史.
诊断成像包括CT和加多增强的MRI.
进行了组织病理学,免疫组织化学和遗传分析 (包括HIST1H3B K37突变).
甲基化分析被用于瘤分类.

主要成果:

鉴定出一种带有脑部侵袭的部分有组织的双边腹膜下体质.
瘤在切除后呈现出快速再生,并被诊断为具有表皮状特征的不可分类的恶性内瘤.
尽管接受了多种治疗 (手术,化疗和放射治疗),但该患者在一年内死于这种疾病.

结论:

儿童中原发性体内瘤异常罕见,但必须在差异诊断中考虑.
用加多增强的MRI揭示了一个突出的增强结节,突出进入大脑外膜是一个关键的发现.
这一案例强调了需要全面的诊断工作,包括分子分析,以准确地分类和管理瘤.

关键词:

在Gd增强的结节.恶性瘤是一种恶性瘤.快速重生,重新生长.肌底体质量肌底体质量

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