中国的急性角关闭和失明:多中心对治疗有效性和视觉结果的回顾性研究
Xiaojie Wang1, Aijun Tian2, Shaodan Zhang1
1National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Ophthalmology. Glaucoma
|February 2, 2026
概括
治疗后急性闭角 (AAC) 失明率显著下降,但延迟呈现仍然是一个主要问题. 早期获得护理对于预防视力损失至关重要,因为这种眼科紧急情况.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 临床研究 临床研究
背景情况:
- 急性角关闭 (AAC) 是一种危急的眼科紧急情况,有可能导致不可逆转的失明.
- 与AAC相关的失明发生率和结果的当前趋势需要当代调查.
研究的目的:
- 分析中国AAC相关失明的发病率,临床特征和管理结果.
- 评估治疗对AAC患者视力敏度和失明率的影响.
主要方法:
- 一项多中心的,回顾性观察性研究,涉及来自中国23家医院的2626名AAC患者.
- 在三个不同的时期 (2020-2023) 收集的数据包括患者人口统计,治疗时间表和视力敏度结果 (CDVA,UDVA).
- 用通用估计方程来比较治疗前和治疗后的失明率和视力敏度.
主要成果:
- 整体失明率从介绍时的28.6% (CDVA) 和42.4% (UDVA) 下降到干预后的16.4% (CDVA) 和20.1% (UDVA) (p<0.001).
- 只有34.3%的患者在症状出现后72小时内寻求治疗.
- 激光和手术干预都显著改善了纠正距离视力敏度 (CDVA).
结论:
- 对AAC的积极治疗显著降低了失明率.
- 延迟医疗呈现是导致持续高AAC相关失明率的主要因素.
- 迫切需要改善早期获得护理的举措,以减轻AAC的视力损失.
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