精神分裂症患者的插曲性未来思维干预:影响和神经相关性
Jia-Li Liu1, Jun-Yan Ye1, Tian-Xiao Yang1
1Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
Neuropsychologia
|February 2, 2026
概括
精神分裂症患者通过最佳自我干预改善了情节性未来思维 (EFT). 这种疗法增强了目标导向的想象力,改变了大脑的连接,这表明了新的治疗途径.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 插曲性未来思维 (EFT) 对于目标追求至关重要,但在精神分裂症中受损.
- 个人目标与EFT有关,但它们在精神分裂症干预中的作用未得到充分研究.
- 在精神分裂症中EFT改善的神经支需要进一步调查.
研究的目的:
- 调查最佳可行的基于自我的未来特异性 (BPSFS) 干预措施的有效性,以改善精神分裂症患者的EFT.
- 探索个人目标在促进EFT改进中的作用.
- 检查与BPSFS干预效应相关的神经机制,特别是默认模式网络功能连接.
主要方法:
- 60名精神分裂症患者被随机分配到BPSFS干预组 (n=29) 或对照组 (n=31).
- 干预组接受了为期四周的八次BPSFS培训;对照组接受了心理教育.
- 评估包括EFT任务,未来目标流性和干预前后静止状态fMRI.
主要成果:
- BPSFS干预显著提高了精神分裂症患者的EFT特异性.
- 未来目标流性的改善部分介于BPSFS对EFT的影响.
- 干预组在顶结和额头极之间表现出增加的功能连接,与EFT特异性收益相关.
结论:
- BPSFS干预有效地提高了精神分裂症患者的偶发性未来思维能力.
- 个人目标,特别是未来目标流性,在EFT改进中起着调解作用.
- 在顶结处增强的功能连接可能是BPSFS干预后EFT改进的关键神经机制.
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