为表单管理创建和应用基于价值的框架
Brandyn Wilcox1, Hetalkumari Patel1, Jerry James1
1Department of Pharmacy, University of Texas Southwestern Medical Center, Dallas, TX, USA.
概括
药物配方决策的新价值评估框架 (VAF) 显示了整体良好的评价者间可靠性. 这种工具对非瘤药物具有很好的可靠性,对瘤药物具有中等的可靠性.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 制药政策 制药政策 制药政策
- 药物评估 药物评估
背景情况:
- 正式的决策需要强大的框架来确保价值.
- 现有的方法可能无法充分捕捉机构的优先事项.
- 需要一种标准化的方法来进行一致的药物评估.
研究的目的:
- 开发和验证瘤学和非瘤学药物的新型价值评估框架 (VAF).
- 评估UT西南医疗中心 (UTSW) 的VAF的评价者间可靠性.
主要方法:
- 开发了一个包含机构优先事项和文献示例的VAF.
- 选择了六个标准:有效性,安全性,新性,证据质量,成本和物流.
- 进行了药物专著的回顾性审查 (2021年10月至2024年10月).
- 在三位评审者中使用类内相关系数 (ICC) 评估了评审者之间的可靠性.
主要成果:
- 在UTSW的VAF取得了良好的整体互评分可靠性 (ICC=0.75).
- 对于非瘤学药物 (ICC=0.80) 观察到非常好的可靠性.
- 对瘤学药物发现中等可靠性 (ICC=0.63).
- 个别标准显示可靠性中等至优异.
结论:
- 开发的机构特定的VAF是可靠的药物表格审查.
- 该框架具有良好的整体可靠性,在不同类型的药物中具有不同的水平.
- VAF提供了一种结构化的方法来评估药物价值,用于配方决策.
相关概念视频
Applications of GIS: Disaster Management and Emergency Response
520
Geographic Information System (GIS) technology is essential for risk identification, action prioritization, and resource optimization in critical situations like flooding and earthquakes. By integrating spatial and demographic data, GIS provides a comprehensive framework for emergency response.GIS integrates data layers, like rainfall intensity, topography, elevation profiles, and river levels, to model high-risk flood zones. These layers assess areas susceptible to flooding based on their...
520
Tonsillitis II: Management
429
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
429
Impression Management Techniques I: Managing Appearances
218
Appearance is a multidimensional aspect of self-presentation that encompasses observable attributes such as clothing, grooming, speech, and nonverbal behavior. These elements are often strategically managed to align with socially constructed expectations in different settings. For instance, individuals tailor their appearance during job interviews, social gatherings, or athletic events to meet the perceived norms of those environments.Contextual Adaptation and Social SignalsThe research...
218
Managing Impressions
172
Impression management encompasses individuals' deliberate efforts to shape how others perceive them during social interactions. This behavior is often employed to conform to social norms, secure approval, or pursue specific goals. While it involves selective self-presentation, it is not necessarily deceptive; individuals frequently present authentic aspects of themselves that align with situational demands.Common strategies include:Ingratiation: where individuals use flattery or agreeableness...
172
Management of Insomnia
641
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
641
Cystic Fibrosis: Management
541
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
541


