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Updated: Feb 4, 2026

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在甜菜军中,通过改变利用先前存在的和新突变的变化,正在进行的杀虫剂耐药性演变
Fang Guan1, Bingbing Fang2, Wenjuan Mei2
1State Key Laboratory of Agricultural and Forestry Biosecurity, Department of Entomology, College of Plant Protection, Nanjing Agricultural University, Nanjing 211800, China; School of Agriculture and Biomanufacturing, Zhengzhou University, Zhengzhou 450001, China.
Pesticide biochemistry and physiology
|February 2, 2026
概括
甜菜军 (Spodoptera exigua) 通过先前存在的和新的突变,迅速发展出对杀虫剂的耐药性. 种群基因组学揭示了耐药性突变的软选择性扫描和单一起源,有助于害虫管理策略.
科学领域:
- * 昆虫分子生物学和种群遗传学.
- * 化学生态学和害虫防治.
- * 进化基因组学和适应.
背景情况:
- *了解昆虫害虫对杀虫剂的耐药性演变对于可持续农业至关重要.
- * 推动对杀虫剂快速适应的种群基因组过程在很大程度上是未知的.
- *Spodoptera exigua是一种重要的农业害虫,已经对多种类型的杀虫剂产生了耐药性.
研究的目的:
- * 为了阐明群体基因组过程背后的昆虫杀虫剂耐药性在Spodoptera exigua.
- * 为了确定赋予对阿弗梅克丁,甲酸,甲酸和二化物耐药性的特定突变.
- * 用祖先重组图 (ARG) 来重建这些抗性突变的进化历史和起源.
主要方法:
- *来自中国20个种群的139个Spodoptera exigua个体的全基因组测序.
- *对6种抗性突变的遗传差异化分析和软选择性扫描的识别.
- * 构建祖先重组图 (ARG) 来推断突变起源和进化轨迹.
- *对近同源系的生物测试,以评估特定突变和交叉耐药性的功能影响.
主要成果:
- * 在Spodoptera exigua中发现了六种关键突变,使其对四种杀虫剂类别产生耐药性.
- * 在种群中观察到很少的遗传差异化,这表明了泛基的种群结构.
- * 对于所有六种抗性突变检测到软选择性扫描,至少有五种具有单一起源.
- * 一些耐药性突变在相应的杀虫剂引入之前就出现了,而另一些突变则在之后出现,有时会产生交叉耐药性.
- *观察到复杂的进化动态对二氧化物抵抗突变,随着时间的推移频率的变化.
结论:
- *Spodoptera exigua通过软选择性扫描先前存在的和新出现的突变而发展出抗昆虫剂的耐药性.
- * 种群基因组学,特别是ARG,对于重建害虫的耐药性演变具有强大作用.
- *这些发现提高了准备能力,并为农业害虫抗虫剂的积极管理策略提供了信息.
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