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Updated: Feb 4, 2026

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
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克隆复杂性定义了不同的瘤内在生物学和在扩散大B细胞淋巴瘤的预后

Takahiro Haeno1,2, Kazuko Sakai1,3, Shuji Minamoto1,2

  • 1Kindai University Faculty of Medicine, Department of Genome Biology, Osaka, Japan.

Cancer medicine
|February 2, 2026
PubMed
概括

在扩散性大B细胞淋巴瘤 (DLBCL) 中,内瘤异质性 (ITH) 与较差的结果有关,特别是在激活B细胞 (ABC) 亚型中. 在DLBCL瘤中的克隆复杂性显示出独特的生物特征和突变,影响疾病的发病性.

关键词:
对DNA突变分析进行分析.副本数量的变化 副本数量的变化扩散的大B细胞淋巴瘤基因表达特征 基因表达特征遗传异质性的遗传异质性

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