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Updated: Feb 4, 2026

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达拉图马布在全身性红斑狼:一个单臂的2期试验

Lennard Ostendorf1,2,3,4, Jan Zernicke5, Jens Klotsche1

  • 1German Rheumatology Research Centre (DRFZ), an Institute of the Leibniz Association, Berlin, Germany.

Nature communications
|February 2, 2026
PubMed
概括

达拉图马布有效地降低了抗双链DNA抗体,并改善了系统性红斑狼 (SLE) 患者的临床症状. 这种抗体消耗疗法通过向抗体分泌细胞来管理SLE具有前途.

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Inductance: Single-Phase And Three-Phase Line

Understanding the inductance of transmission lines is crucial for efficient design and operation in electrical power systems. This discussion delves into the inductance characteristics of single-phase two-wire and three-phase three-wire transmission lines with equal phase spacing.
Single-Phase Two-Wire Line:
A single-phase line consists of two solid cylindrical conductors, denoted as x and y. Each conductor carries phasor currents ix and iy, respectively. Given that the sum of these currents is...
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Capacitance: Single-Phase And Three-Phase Line

In electrical power systems, understanding the capacitance of transmission lines is fundamental for efficient operation.
Single-Phase Lines
Consider a single-phase, two-wire transmission line with equal phase spacing energized by a voltage source. One conductor carries a uniform positive charge, while the other carries an equal negative charge. The capacitance C of the line can be derived from the voltage V between the conductors. For a one-meter section of the line, the capacitance is given...
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Single Pipe Systems01:24

Single Pipe Systems

In pipe flow analysis, problems are typically categorized into three types — Type I, Type II, and Type III — based on the known parameters and the desired outcome. Each type of problem addresses specific engineering requirements using fluid properties, pipe characteristics, and operational conditions.
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Power Distribution in Three-phase and Single Phase Circuits01:17

Power Distribution in Three-phase and Single Phase Circuits

Power distribution within electrical circuits is a foundational aspect of residential and industrial energy systems. While single-phase power is common in residential settings, three-phase power is the standard for industrial environments with heavy machinery. Each system is different and has advantages, and it's crucial to understand the underlying principles of power distribution and material efficiency.
Single-Phase Power Distribution:
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Phase I Reactions: Oxidation of Aliphatic and Aromatic Carbon-Containing Systems01:19

Phase I Reactions: Oxidation of Aliphatic and Aromatic Carbon-Containing Systems

Phase I biotransformation reactions are integral to drug metabolism, predominantly involving oxidative, reductive, and hydrolytic transformations. Chief among these are oxidative reactions, which enhance the hydrophilicity of xenobiotics and introduce polar functional groups to facilitate their elimination from the body.
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