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Updated: Feb 4, 2026

Models of Bone Metastasis
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Published on: September 4, 2012

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POM121 O-GlcNAcylation通过增强的c-MYC核导入和ECM重编程,促进非小细胞肺癌的骨转移

Yi-Zhe Ren1, Ming-Na Zhao1, Feng-Lin Du2

  • 1Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Oncogene
|February 2, 2026
PubMed
概括

一项新的研究揭示了非小细胞肺癌 (NSCLC) 如何扩散到骨. 研究人员确定了OGT-POM121-c-MYC-ECM通路,这是骨转移的关键驱动因素,提供了潜在的新诊断和治疗点.

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