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Updated: Feb 4, 2026

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
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Published on: December 16, 2022

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杂交小鼠模型中的加速和局部同核病变:对正子发射断层扫描研究的含义研究

Chunfang A Xia1, Hsiu-Ming Tsai2, Sandra Diaz Garcia3

  • 1Discovery Technologies and Molecular Pharmacology, Johnson & Johnson, San Diego, CA, USA. cxia1@its.jnj.com.

Npj imaging
|February 2, 2026
PubMed
概括

这项研究引入了一种新的AAV/PFF杂交小鼠模型,可以快速复制帕金森病 (PD) 的病理,包括α-synuclein聚合和神经元损失. 这种模型加速了针对同核蛋白病变和PET成像开发的临床前研究.

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