绝经后妇女的结肠镜的诊断价值:一项回顾性研究
1Shanxi University of Medicine, Fenyang, Shanxi, 032200, China. Tglp201203@163.com.
BMC women's health
|February 3, 2026
概括
阴性HPV 16/18和非典型细胞学结果的绝经后妇女可以接受例行监测. 像阴道出血这样的症状需要立即评估宫癌风险.
科学领域:
- 妇科 妇科 妇科 妇科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 绝经后妇女的生理变化会影响宫癌查的准确性.
- 在这个人口群体中评估宫内皮质瘤 (CIN) 风险至关重要.
研究的目的:
- 评估非16/18高风险HPV和非典型细胞学 (NILM/ASC-US) 的绝经后妇女的CIN风险.
- 在这个人群中检查查和结肠镜检查的临床影响.
- 确定改进诊断协议的方法.
主要方法:
- 分析了异常细胞学或HPV (2023年1月至2024年12月) 的绝经后妇女的临床数据.
- 用NILM或ASC-US细胞学对HPV16/18阳性和非HPV16/18阳性组之间的CIN发病率进行比较.
- 对于非HPV16/18阳性的女性进行详细的结肠镜分析,这些女性患有NILM/ASC-US.
主要成果:
- 在392名非HPV16/18阳性患者中 (NILM/ASC-US),12.76%患有CIN 1,4.59%患有CIN 2/3,0.26%患有宫癌.
- 在NILM的4.81%和ASC-US子组的5.00% (p=0.94) 中发生了CIN 2+病变.
- 25.96%的CIN 2+病例呈现出绝经后出血或异常分泌.
结论:
- 绝经后妇女的阴道出血/排泄需要立即评估.
- 对于具有NILM/ASC-US细胞学NILM/ASC-US细胞学的HPV 16/18阴性绝经后患者,常规监测是适当的.
- 考虑辅助测试,如E6/E7mRNA或p16/Ki-67;异常结果需要进一步处理.
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