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Updated: Feb 4, 2026

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
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Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer

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在体外证据和综合生物信息学确定SGLT2-PPARγ轴作为针对结直肠癌细胞中聚乙烯微塑料驱动的代谢重编程的目标

Isabella Donisi1, Celestino Sardu2,3, Antonino Colloca1

  • 1Department of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. De Crecchio 7, 80138, Naples, Italy.

Journal of translational medicine
|February 3, 2026
PubMed
概括

聚乙烯微塑料通过增加增殖和改变新陈代谢,恶化结直肠癌 (CRC) 的生长. 针对SGLT2的治疗或涉及玛-丁和L-卡尼丁的治疗显示出减轻这些有害影响的希望.

关键词:
结肠直肠癌是一种癌症.聚乙烯-微塑料聚乙烯-微塑料四次性化合物 四次性化合物这是一种SGLT2抑制剂.

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